Description

Job Description

The Sahoo Lab at the Fralin Biomedical Research Institute studies the genetic and functional mechanisms that drive bone marrow failure, clonal hematopoiesis, and progression to MDS and AML. We integrate genomic and functional approaches on patient derived samples, iPSC and mouse disease models to uncover mechanisms and therapeutic vulnerabilities.
Current project areas include:
1. Germline predisposition to MDS and AML: mechanisms by which inherited mutations cause hematopoietic failure and predispose to leukemogenesis
2. Chromosome 7 aneuploidy syndromes: modeling monosomy 7 associated bone marrow failure and its role in clonal selection
3. Clonal evolution and therapeutic vulnerabilities: using single cell sequencing to track clonal dynamics and to identify targets in high risk MDS and AML
Position Summary: We seek a full-time Research Associate to support cellular and in vivo studies. The role requires strong proficiency in wet-lab techniques, including molecular biology and mammalian cell culture. Experience with induced pluripotent stem cells is required. Mouse handling for hematopoietic studies is also required. Candidates without prior experience must be clearly willing to learn.

Required Qualifications

• Master's degree in biology and significant professional experience and equitable laboratory experience
• Expertise in experimental design and execution
• Effective organizational and time management skills
• Ability to work independently and as part of a collaborative team
• Excellent communication skills
• Extensive primary cell culture expertise

Preferred Qualifications

• Experience with general mouse hematopoiesis and hematopoietic cancer models
• Familiarity with CRISPR-based genome editing and functional screens

Overtime Status

Exempt: Not eligible for overtime

Appointment Type

Restricted

Salary Information

Commensurate with experience

Hours per week

40+

Review Date

10/10/25

Additional Information

The successful candidate will be required to have a criminal conviction check.

About Virginia Tech

Dedicated to its motto, Ut Prosim (That I May Serve), Virginia Tech pushes the boundaries of knowledge by taking a hands-on, transdisciplinary approach to preparing scholars to be leaders and problem-solvers. A comprehensive land-grant institution that enhances the quality of life in Virginia and throughout the world, Virginia Tech is an inclusive community dedicated to knowledge, discovery, and creativity. The university offers more than 280 majors to a diverse enrollment of more than 36,000 undergraduate, graduate, and professional students in eight undergraduate colleges, a school of medicine, a veterinary medicine college, Graduate School, and Honors College. The university has a significant presence across Virginia, including Blacksburg, the greater Washington, D.C. area, the Health Sciences and Technology Campus in Roanoke, sites in Newport News and Richmond, and numerous Extension offices and research institutes. A leading global research institution, Virginia Tech conducts more than $650 million in research annually.

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If you are an individual with a disability and desire an accommodation, please contact Brittany Shelton at sheltb@vtc.vt.edu during regular business hours at least 10 business days prior to the event.

Advertised: September 26, 2025
Applications close: