Description

Site Name: USA - Pennsylvania - King of Prussia
Posted Date: May 13 2026

The Sr. MES Engineer will provide engineering and technical support for manufacturing execution systems in the Biopharmaceutical Operations facility. Evaluate and develop technology, plan and implement modifications, troubleshoot and support manufacturing execution systems, and assist in night shift troubleshooting activities during processing operations.

This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

• Provide technical leadership in support of MES (Emerson Syncade and InfoLog) systems and network infrastructure, including electronic batch records, ensuring business continuity and compliance.
• Collaborate with building stakeholders throughout the automation lifecycle: gather system/end user requirements; complete design, implementation, and testing/validation of changes; maintain documentation; maintain and monitor various systems.
• Provide subject matter expertise and technical ownership of MES deployments and associated systems.
• Plan, prioritize, and manage updates to the execution system designs due to process changes, audits, and CAPA actions through collaboration with organization stakeholders.
• Work in a way that models respect for safety and EHS, quality compliance, data integrity, and engineering standards.
• Troubleshoot and resolve real-time operational issues, supporting global Tech and automation staff.
• Support visualization and accessibility of aggregate data using tools like PowerBI, InfoBatch, and SQL.
• Build relationships across Production, Quality, and Global Tech teams to establish robust communication processes.
• Represent MES systems in regulatory inspections and provide user support for technical issues.
• Troubleshoot and diagnose problems with manufacturing execution systems; generate recommendations and then develop/execute solutions to correct and resolve.
• Adhere to, develop, and continuously improve the operation and maintenance procedures for manufacturing execution systems.
• Support the maintenance and upkeep of the operational technology environment through administration of systems, networks, databases, and accounts. This includes servers, hosts, and analytical equipment.
• Support site technology related to systems integration and digital transformation initiatives. Stay current with developments in the field of controls and manufacturing execution systems.
• Lead and develop those around you through active engagement with stakeholders and by modeling professional behaviors.

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

• BS/BA in engineering, life sciences, biology or equivalent technical discipline
• 4+ years of experience in design, programming, start-up, and troubleshooting of manufacturing execution systems (Syncade)

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• Ability to diagnose problems, generate options, prioritize issues, select optimal solutions, and implement decisions/resolve problems
• A demonstrated ability to interact well with peers and senior personnel in multidisciplinary teams involving scientific, engineering, and operational disciplines
• Experience in systems/account administration, network design, and server troubleshooting
• Experience coding Visual Basic and similar languages
• Experience working in a GMP environment
• Experience in the design, programming, start-up, and troubleshooting of PLC (Allen Bradley) or DCS (DeltaV) systems
• Knowledge in current standards of control system platforms and computer system validation

#LI-GSK

Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases - to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at - usrecruitment.adjustments@gsk.com

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

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